InhaltsangabePreface PART I: Basic Methodology INFRARED AND RAMAN INSTRUMENTATION FOR MAPPING AND IMAGING Introduction to Mapping and Imaging MidInfrared Microspectroscopy and Mapping Raman Microspectroscopy and Mapping NearInfrared Hyperspectral Imaging Raman Hyperspectral Imaging MidInfrared Hyperspectral Imaging Mapping with Pulsed Terahertz Radiation Summary CHEMOMETRIC TOOLS FOR IMAGE ANALYSIS Introduction Hyperspectral Images: The Measurement Image Preprocessing Exploratory Image Analysis Quantitative Image Information: Multivariate Image Regression (MIR) Image Segmentation Image Resolution Future Trends PART II: Biomedical Applications VIBRATIONAL SPECTROSCOPIC IMAGING OF SOFT TISSUE Introduction Preparation of Soft Tissue for Vibrational Spectroscopic Imaging Applications to Soft Tissue Conclusions VIBRATIONAL SPECTROSCOPIC ANALYSIS OF HARD TISSUES Introduction Importance of Tissue Age versus Specimen Age FTIR Spectroscopy Raman Spectroscopy Clinical Applications of Raman Spectroscopy MEDICAL APPLICATIONS OF INFRARED SPECTRAL IMAGING OF INDIVIDUAL CELLS Introduction Methods Results and Discussion Future Potential of SCP/Conclusions PART III: Agriculture, Plants, and Food INFRARED AND RAMAN SPECTROSCOPIC MAPPING AND IMAGING OF PLANT MATERIALS Introduction, Background, and Perspective Application of Mapping and Imaging to Horticultural Crops Application of Mapping and Imaging to Agricultural Crops Mapping and Imaging of Wild Plants and Trees Application of Mapping and Imaging to Algae Interaction Between Plant Tissue and Plant Pathogens NIR HYPERSPECTRAL IMAGING FOR FOOD AND AGRICULTURAL PRODUCTS Introduction HSI as a "Super" NIR Analyzer NIR HS Imager as a "Super" Vision System Conclusion PART IV: Polymers and Pharmaceuticals FTIR AND NIR SPECTROSCOPIC IMAGING: PRINCIPLES, PRACTICAL ASPECTS, AND APPLICATIONS IN MATERIAL AND PHARMACEUTICAL SCIENCE Introduction Instrumentation for NIR and FT-IR Imaging Applications of FT-IR and FT-NIR Imaging for Polymer Characterization NIR Imaging Spectroscopy for Quality Control of Pharmaceutical Drug Formulations FTIR Spectroscopic Imaging of Inorganic Materials FTIR IMAGING IN ATR AND TRANSMISSION MODES: PRACTCAL CONSIDERATIONS AND EMERGING APPLICATIONS FTIR Imaging: Introduction FTIR Imaging: Technical Considerations Practical Applications Conclusion and Outlook TERAHERTZ IMAGING OF DRUG PRODUCTS Introduction Low Wavenumber Region in the Infrared Spectrum THzTDS Technology and Applications THz Imaging in the Pharmaceutical Industry Going Forward Competition versus Cost: A Challenge for the Future Conclusion PART V: Imaging Beyond the Diffraction Limit SPECTROSCOPIC IMAGING OF BIOLOGICAL SAMPLES USING NEAR-FIELD METHODS TipEnhanced Raman Scattering (TERS) Detection of Biomolecules Biopolymers Membranes, Viruses, and Bacteria Conclusion INFRARED MAPPING BELOW THE DIFFRACTION LIMIT Introduction and Description of Early Work NearField Microscopy by Elastic Scattering from a Tip PART VI: Developments in Methodology SUBSURFACE RAMAN SPECTROSCOPY IN TURBID MEDIA Introduction Techniques for Deep Noninvasive Raman Spectroscopy Examples of Application Areas Conclusions NONLINEAR VIBRATIONAL SPECTROSCOPIC MICROSCOPY OF CELLS AND TISSUE Introduction Principles of Nonlinear Optical Imaging Instrumentation for Multimodal Nonlinear Microscopy Applications WIDEFIELD FTIR 2D AND 3D IMAGING AT THE MICROSCALE USING SYNCHROTRON RADIATION Introduction Optical Evaluation Mathematical Evaluation of Hyperspectral Cubes Widefield versus Raster Scanning Geometries Examples Conclusions Index

Reiner Salzer is Professor Emeritus of Analytical Chemistry at the Dresden University of Technology (Germany). He has authored almost 300 publications and serves on various national and international scientific boards. Professor Salzer is a member of the Norwegian Academy of Science and a recipient of the Emich Plaque of the Austrian Society of Analytical Chemistry. Recently he also received the Clemens Winkler Medal of the GDCh (German Chemical Society), the Hanus Medal of the Czech Chemical Society and the Ioannes Marcus Marci Medal of the Czech Spectroscopic Society. Professor Salzer served as President of the Division Analytical Chemistry of the GDCh and is National Delegate to the Division Analytical Chemistry of EuCheMS, where he is Head of the Study Group Education. He is Chairman of the ECTN Label Committee for the Quality Eurolabels in Chemistry Education. Heinz W. Siesler is Professor Emeritus of Physical Chemistry at the University of Duisburg-Essen (Germany). After receiving his PhD in chemistry from the University of Vienna (Austria), he worked as a postdoctoral fellow at the University of Cologne (Germany) and as a lecturer at the Witwatersrand University (Johannesburg, South Africa). Prior to his academic position, he gained industrial experience as section head in molecular spectroscopy and thermal analysis in the Corporate R&D Department of Bayer AG (Dormagen, Germany). Between 1992 and 2010 he held guest professorships in France, Japan, and Austria. Professor Siesler is a recipient of the EAS Award, the Tomas Hirschfeld Award and the Buechi Award in near-infrared spectroscopy and he is a Fellow of the Society for Applied Spectroscopy. His main research focuses on the application of vibrational spectroscopy to chemical and polymer research, analysis and quality control, and he has authored more than 230 publications in this field.

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